Simparica Trio Green 20.1-40kg
| Price Per per chewable tablet (not box): | $ 30.08 |
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| Dispensing Fee: | $ 4.99 |
| Standard Package Size: | 6 |
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This is a prescription item and its sale is subject to verification of prescriptions on file and/or the authorization of a prescribing veterinarian. |
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| DIN#: | 02492695 |
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| Strength: | 48/0.96/200mg |
| Dosage Form: | per chewable tablet (not box) |
| Package Size: | 6 |
| Refrigerate: | No |
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| LMA: | No |
| Manufacturer: | Zoetis |
| Active Ingredients: | sarolaner/moxidectin/pyrantel |
What This Medication Is Used For
Simparica Trio green chewables are a once-monthly, veterinarian-prescribed treatment for large dogs. This strength is formulated for dogs weighing between 20.1 kg and 40 kg and is designed to provide broad parasite protection in a single dose.
It combines protection against both internal and external parasites, helping reduce the need for multiple medications.
Parasites it targets
Fleas
Ticks
Heartworm (prevention)
Roundworms and hookworms
When dogs may need treatment
Ongoing scratching, biting, or skin irritation linked to fleas
Tick exposure after time outdoors
Living in or travelling to areas with higher parasite risk
Why your veterinarian may prescribe it
To simplify parasite prevention into one monthly chew
To maintain consistent protection across seasons
To align treatment with your dog’s environment and lifestyle
How It Works
Simparica Trio works from inside your dog’s body after it is swallowed. Each ingredient plays a different role in controlling parasites.
One ingredient kills fleas quickly and helps control ticks
One helps prevent heartworm disease by stopping development
One treats and controls intestinal worms such as roundworms and hookworms
This approach allows one chew to cover multiple parasite types at the same time.
It does not treat parasites in your home or yard. If there is an active infestation, your veterinarian may recommend additional steps such as environmental treatment.
Compared to single-purpose products
Some treatments focus on only fleas or only internal parasites. This option combines several types of protection into one monthly dose when appropriate.
Ongoing prevention
Parasite risks change based on location, travel, and time of year. Your veterinarian may adjust your dog’s plan over time to maintain protection.
Dosage and Strength Information
Your veterinarian determines the correct dosing based on your dog’s weight and health history. Follow their instructions closely and do not change the schedule on your own.
About this strength
The green 20.1–40 kg chew is made for large dogs. It delivers the correct balance of active ingredients for this weight range in a single monthly chew.
Other Simparica Trio strengths
Safety Information and Possible Side Effects
Like any medication, side effects are possible. Most are mild and short-term.
Common observations may include
Vomiting
Diarrhoea
Reduced appetite
Temporary low energy
Contact your veterinarian if you notice
Ongoing vomiting or diarrhoea
Changes in behaviour or activity levels
Signs of an allergic reaction such as swelling or hives
Important considerations
For dogs only
Puppies must be at least 8 weeks old and meet the weight requirement
Use only under veterinary guidance
Prescription Requirements in Canada
Simparica Trio is a prescription medication in Canada. A valid veterinary prescription is required before the product can be dispensed.
How prescriptions are handled
Your veterinarian can send the prescription directly to the pharmacy
The pharmacy can contact your veterinarian for approval
Uploaded prescriptions must be followed by the original copy
Orders are processed only after prescription approval is confirmed.
Shipping and Fulfilment Information
Orders are prepared once prescription verification is complete and stock is available.
Shipping details
Delivered through Canada Post
Signature or pickup at a postal outlet may be required
Tracking is provided after dispatch
Processing information
Payment is processed when the order is ready to ship
Delivery timelines begin after dispatch
Timing may vary depending on prescription approval and inventory
Pricing notes
Pricing is listed per chewable tablet
A dispensing fee applies
Standard packaging often includes six chewables
Frequently Asked Questions
Can I buy Simparica Trio green without a prescription?
No. A valid prescription is required in Canada before this product can be dispensed.
What makes this different from other parasite treatments?
It combines flea, tick, heartworm, and intestinal worm protection in one monthly chew instead of using multiple products.
Is Simparica Trio safe for cats?
No. This product is formulated only for dogs. Speak with your veterinarian for cat-specific options.
What if my dog reacts after taking it?
Contact your veterinarian, especially if symptoms such as vomiting, diarrhoea, or unusual behaviour continue.
Does my dog need a heartworm test first?
Your veterinarian may recommend testing based on your dog’s history, risk level, and location.