Simparica Trio Brown 40.1-60kg
| Price Per per chewable tablet (not box): | $ 30.73 |
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| Dispensing Fee: | $ 4.99 |
| Standard Package Size: | 6 |
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This is a prescription item and its sale is subject to verification of prescriptions on file and/or the authorization of a prescribing veterinarian. |
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| DIN#: | 02492709 |
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| Strength: | 72/1.44/300mg |
| Dosage Form: | per chewable tablet (not box) |
| Package Size: | 6 |
| Refrigerate: | No |
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| LMA: | No |
| Manufacturer: | Zoetis |
| Active Ingredients: | sarolaner/moxidectin/pyrantel |
What This Medication Is Used For
Simparica Trio brown tablets are a monthly, veterinarian-prescribed chewable designed to deliver complete parasite coverage for extra-large dogs. This strength is intended for dogs weighing 40.1 kg to 60 kg, helping provide broad protection against both internal and external parasites with a single monthly dose.
Parasites it protects against
Flea infestations
Tick infestations
Heartworm disease (prevention)
Certain intestinal roundworms and hookworms
Typical scenarios before treatment
Persistent biting, scratching, or skin irritation linked to fleas
Detection of ticks after outdoor exposure
Increased parasite risk because of regional conditions, travel, or lifestyle
Why a veterinarian may recommend it
When consolidated monthly parasite protection fits your dog’s needs
To streamline preventive care without multiple products
To match parasite prevention plans with lifestyle and environmental risks
How It Works
Simparica Trio works systemically once ingested, meaning it distributes through your dog’s body to target different parasite categories:
One active component begins killing fleas and ticks soon after administration.
Another helps prevent heartworm disease by interrupting the parasite’s life cycle.
A third treats and helps control certain intestinal worms, such as roundworms and hookworms.
This chewable works from within and does not directly remove parasites in your dog’s surroundings. In cases where there is active infestation, your veterinarian may also recommend environmental control measures.
How it compares to single-target products
Some preventatives only address external or internal parasites. Simparica Trio combines broad-spectrum protection in one tablet when your veterinarian determines it is appropriate for your dog’s prevention plan.
Use in ongoing parasite plans
Parasite exposure can change with season, travel, climate, and local prevalence. Veterinarians can reassess and adjust prevention strategies over time to maintain optimal protection.
Dosage and Strength Information
Your veterinarian will decide the correct dosage and frequency based on your dog’s weight and health profile. Never change the dose or schedule without veterinary approval.
About this strength
The brown 40.1–60 kg strength is specifically formulated for very large dogs to ensure that the active ingredients are proportional and effective for comprehensive protection in a once-monthly chew.
Other Simparica Trio strengths
Safety Information and Possible Side Effects
Side effects may occur with any medication and can vary by dog. Some dogs may experience mild digestive upset such as vomiting or diarrhoea, transient lethargy, or decreased appetite.
Contact your veterinarian if you observe
Vomiting or diarrhoea that persists or worsens
Significant changes in behaviour, activity, or appetite
Signs of a potential allergic reaction such as swelling or hives
Important use considerations
Simparica Trio is intended for canine use only and should not be administered to other species. Puppies must be at least 8 weeks old and meet the minimum weight requirement before this medication can be used. Your veterinarian will review your dog’s health status and history before prescribing.
Prescription Requirements in Canada
Simparica Trio is a prescription medication under Canadian regulations. A valid veterinary prescription and authorisation are required before this product can be dispensed and shipped.
How prescriptions are processed
Your veterinarian may fax or call the prescription directly to the pharmacy
The pharmacy can contact your veterinarian for authorisation if requested
If you upload a copy of the prescription, the original must be mailed before fulfilment
Prescription orders are held until authorisation is confirmed.
Shipping and Fulfilment Information
Orders are prepared for shipment once prescription review is complete and the product is in stock.
Shipping and handling
Shipped via Canada Post
Prescription items may require proof of delivery and can be carded for pickup at your local postal outlet
Tracking details are provided once your order is dispatched
Processing notes
Card payments are processed when the order is ready for shipment
Delivery timelines start once the parcel leaves the pharmacy and may vary with prescription verification and stock availability
Pricing details
Pricing is shown per chewable tablet. A dispensing fee applies. Standard packaging typically contains six chewable tablets.
Frequently Asked Questions
Can I purchase Simparica Trio brown without a prescription?
No. In Canada, this product requires a valid veterinary prescription before dispensing.
How does Simparica Trio compare with other parasite preventatives?
Simparica Trio offers integrated protection against fleas, ticks, heartworm, and specific intestinal parasites in one monthly chew. This differs from products that focus solely on one category of parasite.
Is this medication safe for cats?
No. Simparica Trio is formulated for dogs only. Talk to your veterinarian about appropriate parasite prevention for cats.
What should I do if my dog seems unwell after taking the chew?
Contact your veterinarian for advice, particularly if vomiting, diarrhoea, lethargy, or other concerning signs occur.
Do I need heartworm testing before starting this medication?
Your veterinarian may recommend heartworm testing based on your dog’s risk profile, location, and history. Follow their professional advice.